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The 2021 NFL regular season is finally here, which means it's time to win money. Well, you'll win money, because you have come to the right place when it comes to expert picks against the spread. While your friends are losing money on favorites they were certain would cover in Week 1, you did your research and knew better. This is your study guide, compiled by the experts.Each week, we'll collect all of the best picks and gambling content from CBSSports.com and SportsLine in one place, so you can get picks against the spread from our CBS Sports experts as well as additional feature content for each game, including plays from top SportsLine experts and the SportsLine Projection Model, best bets from our staff, survivor picks and more. Enjoy our run-through of a busy Week 1! All odds via Caesars Sportsbook.Time:Sunday, 1 p.m. ET (CBS), stream on Paramount+ ()Open:Titans -2.5, O/U 51.5Current:Titans -3, O/U 53.5 "This was my upset call during my early look-ahead story from a few weeks back and I continue to like the spot the Cardinals are in to begin the season. They have an offense littered with weapons and a quarterback in Kyler Murray that should be able to avoid whatever pre sure the Titans are able to apply as they look to improve in that area following a dreadful 2020 season on that side of the ball. Meanwhile, both of Tenne see's top two receivers A.J. Brown and Julio Jones have been limited throughout the summer due to various injuries. While I expect both to play, I'm not quite sure they'll be 100%, which will hurt Ryan Tannehill's chances of succe s in the pa sing game."Meanwhile, Tenne see is another team that has historically struggled out of the gate. In its last five Domingo Santana Jersey Week 1 contests, the Titans are 1-4 ATS and 1-5 ATS in their last six games in September."CBS Sports NFL writer Tyler Sullivan is calling an upset! Check out the rest of his Week 1 picks, . Pete Prisco Jason La Canfora Will Brinson Jared Dubin Ryan Wilson John Breech Dave Richard Jamey Eisenberg Cardinals at Titans (-3) Time:Sunday, 1 p.m. ET (CBS), stream on Paramount+ ()Open:Jaguars -2, O/U 46Current:Jaguars -3, O/U 45.5SportsLine's Mike Tierney is all over teasers this season. If you're unfamiliar, a teaser is a play that involves at least two games with more favorable point spreads than are offered with a traditional bet. Our picks will be limited to two-game, six-point teasers, meaning that a half-dozen points will be tacked on in favor of our chosen team in each game.We can tell you he likes teasing the Texans up to +9. Milwaukee Brewers Blank Jersey to see what else he's suggesting. Pete Prisco Jason La Canfora Will Brinson Jared Dubin Ryan Wilson John Breech Dave Richard Jamey Eisenberg Jaguars (-3) at Texans Time:Sunday, 1 p.m. ET (CBS), stream on Paramount+ ()Open:Chargers -2, O/U 44.5Current:Washington -1, O/U 44.5"Justin Herbert has never played a game in an NFL stadium against an NFL defense with a full crowd cheering against him and being loud and being raucous. That should be a factor for him, Burrow and Tua. Not only that, but you're dealing with a new offense, and a new offensive coordinator and so all that coordination that you were able to do easily in empty stadiums is now suddenly going to be much, much more difficult and I think we could see Herbert struggle a little bit against an elite defense. So give me Washington all day. Love the Football Team here."That's Will Brinson's take from the Pick Six Podcast, where he, Pete Prisco and R.J. White broke down all the games from a gambling perspective and gave out best bets on Friday -- as they do every week. Give it a listen below andin your feed daily. Pete Prisco Jason La Canfora Will Brinson Jared Dubin Ryan Wilson John Breech Dave Richard Jamey Eisenberg Chargers (-1) at Washington Time:Sunday, 1 p.m. ET (Fox), stream on fuboTV ()Open:Vikings -3, O/U 47Current:Vikings -3, O/U 47"Kirk Cousins has done a very good job this offseason making the Minnesota Vikings unattractive from a season-long betting perspective, but that won't matter in this game. Joe Burrow is back but is he BACK? We haven't seen him confidently working the pocket the way we expect. Ja'Marr Chase's drops are a concern but I think he'll end up being fine. The bigger problem here is Cincy probably can't slow down the Vikings rushing attack. This is a Dalvin Cook smash spot out of the gate against a bad defense with an improved offensive line. I think Minnesota gets the lead and leans into it aggre sively. If you disagree, take it up with Vegas: Dalvin's rush prop at Caesar's is 95.5! That's a bit too rich for Week 1 but I would still Josh Hader Jersey lean over on it."CBS Sports' Will Brinson is on the Vikings, and also is offering up a free Dalvin prop as well! Check out all of his Week 1 picks, . Pete Prisco Jason La Canfora Will Brinson Jared Dubin Ryan Wilson John Breech Dave Richard Jamey Eisenberg Vikings (-3) at Bengals Time:Sunday, 1 p.m. ET (CBS), stream on Paramount+ ()Open
anthers -3.5, O/U 43.5Currentanthers -4, O/U 45"Even as this line has fluctuated, I'd still lean toward Carolina as this number should probably sit somewhere around six. The Jets are coming into this game after a 2-14 regular season a year ago and will be sporting a first-year head coach along with a rookie quarterback. Not only that, but New York's pa s-catching unit is a little dinged up with(COVID) already ruled out anddealing with a knee injury. Meanwhile, you have a Panthers offense that boasts an extremely motivated Darnold, who'll have weapons like,, andat his disposal. Even if you don't want to lay the points, this should be a solid moneyline look at -210."Our own Tyler Sullivan on Burch Smith Jersey why he likes Carolina on Sunday. He actually created a gambling guide on this matchup with analysis on the Total and suggested player props as well. Check it out, . Pete Prisco Jason La Canfora Will Brinson Jared Dubin Ryan Wilson John Breech Dave Richard Jamey Eisenberg Jets at Panthers (-5) Time:Sunday, 1 p.m. ET (Fox), stream on fuboTV ()Open:Falcons -4, O/U 47.5Current:Falcons -3.5, O/U 48.5 "I am trying to figure out why the Falcons are the favorite, outside of them playing at home. But when you consider how many debacles they have had in front of their own fans, how hospitable their dome has been to opponents and the Falcons' disturbing trend of waiting until November to start playing with a pulse, it's hard to favor them. Is new rookie coach Arthur Smith going to cure all of that in his first game? I strongly favor the Eagles personnel in the trenches on both sides -- offensive and defensive line -- and their multiplicity in the run game should be a problem for a perennially suspect Atlanta front seven.does not fare well under pre sure at this point, and I suspect he is forced to pick up his feet more than he would like Sunday. Both teams have brand new young coaches, but I favor the guy on the road who doesn't feel like he needs to put on a show or unveil all of his offensive tricks and bells and whistles. This would be a moneyline play for me. I like the dog to win."CBS Sports NFL Insider Jason La Canfora feels like the wrong team is favored in this matchup. Check out his other best Week 1 bets, . Pete Prisco Jason La Canfora Will Brinson Keston Hiura Jersey Jared Dubin Ryan Wilson John Breech Dave Richard Jamey Eisenberg Eagles at Falcons (-3.5) Time:Sunday, 1 p.m. ET (CBS), stream on Paramount+ () Open:Bills -5.5, O/U 51Current:Bills -6.5, O/U 48"Ben Roethlisberger looked like a shell of himself last season, but I was very impre sed with him in his limited action against the Lions in the preseason. All reports out of Pittsburgh have him turning back the clock. Unfortunately, I don't trust his offensive line yet, and I think the offense is going to be a work in progre s. The Bills second-teamers nearly relegated the Bears first-teamers last month. Buffalo keeps it r
anthers -3.5, O/U 43.5Currentanthers -4, O/U 45"Even as this line has fluctuated, I'd still lean toward Carolina as this number should probably sit somewhere around six. The Jets are coming into this game after a 2-14 regular season a year ago and will be sporting a first-year head coach along with a rookie quarterback. Not only that, but New York's pa s-catching unit is a little dinged up with(COVID) already ruled out anddealing with a knee injury. Meanwhile, you have a Panthers offense that boasts an extremely motivated Darnold, who'll have weapons like,, andat his disposal. Even if you don't want to lay the points, this should be a solid moneyline look at -210."Our own Tyler Sullivan on Burch Smith Jersey why he likes Carolina on Sunday. He actually created a gambling guide on this matchup with analysis on the Total and suggested player props as well. Check it out, . Pete Prisco Jason La Canfora Will Brinson Jared Dubin Ryan Wilson John Breech Dave Richard Jamey Eisenberg Jets at Panthers (-5) Time:Sunday, 1 p.m. ET (Fox), stream on fuboTV ()Open:Falcons -4, O/U 47.5Current:Falcons -3.5, O/U 48.5 "I am trying to figure out why the Falcons are the favorite, outside of them playing at home. But when you consider how many debacles they have had in front of their own fans, how hospitable their dome has been to opponents and the Falcons' disturbing trend of waiting until November to start playing with a pulse, it's hard to favor them. Is new rookie coach Arthur Smith going to cure all of that in his first game? I strongly favor the Eagles personnel in the trenches on both sides -- offensive and defensive line -- and their multiplicity in the run game should be a problem for a perennially suspect Atlanta front seven.does not fare well under pre sure at this point, and I suspect he is forced to pick up his feet more than he would like Sunday. Both teams have brand new young coaches, but I favor the guy on the road who doesn't feel like he needs to put on a show or unveil all of his offensive tricks and bells and whistles. This would be a moneyline play for me. I like the dog to win."CBS Sports NFL Insider Jason La Canfora feels like the wrong team is favored in this matchup. Check out his other best Week 1 bets, . Pete Prisco Jason La Canfora Will Brinson Keston Hiura Jersey Jared Dubin Ryan Wilson John Breech Dave Richard Jamey Eisenberg Eagles at Falcons (-3.5) Time:Sunday, 1 p.m. ET (CBS), stream on Paramount+ () Open:Bills -5.5, O/U 51Current:Bills -6.5, O/U 48"Ben Roethlisberger looked like a shell of himself last season, but I was very impre sed with him in his limited action against the Lions in the preseason. All reports out of Pittsburgh have him turning back the clock. Unfortunately, I don't trust his offensive line yet, and I think the offense is going to be a work in progre s. The Bills second-teamers nearly relegated the Bears first-teamers last month. Buffalo keeps it r